BDBM50396018 CHEMBL1230640

SMILES OC(=O)c1ccc(O)c2ncccc12

InChI Key InChIKey=JGRPKOGHYBAVMW-UHFFFAOYSA-N

Data  36 IC50  1 Kd  1 EC50

PDB links: 7 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50396018   

TargetLysine-specific demethylase 4A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of recombinant human JMJD2A using biotinylated histone H3 as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataEC50:  8.70E+4nMAssay Description:Inhibition of human Flag-tagged KDM4A expressed in human HeLa cells assessed as increase in H3K9me3 level after 24 hrs by DAPI staining based immunof...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of JMJD2A catalytic domain by mass spectrophotometric analysisMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of N-terminal His-tagged human KDM4A using ARK(me3)STGGK peptide as substrate preincubated for 15 mins followed by susbtrate addition meas...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50:  200nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli and measured after 1 hrs by alpha screen assayMore data for this Ligand-Target Pair